What it is
A synthetic GHRH analog stabilized by an N-terminal trans-3-hexenoic acid modification. Supplied as a lyophilized powder.
How it works
Binds and activates pituitary GHRH receptors, stimulating endogenous growth hormone release and downstream IGF-1 production.
Where it's used
Used in HIV-associated lipodystrophy to reduce excess abdominal fat.
FDA-approved use
Reduction of excess abdominal fat in HIV-infected adult patients with lipodystrophy.
Reconstitution
Supplied as a lyophilized powder; reconstituted with the supplied sterile water for injection prior to subcutaneous administration.
Tracking it
Tesamorelin is injectable, so two things matter in a log: when you dosed and where. Rotating sites and writing both down prevents the classic “did I already pin the left side?” problem. with a half-life of about 30 minutes, a dose log also lets a tracker model the relative amount still in your system between doses.
Source
OpenFDA
Last reviewed 2026-06-11