What it is
A synthetic pentadecapeptide (15 amino acids) derived from a partial sequence of a protective protein found in human gastric juice. Supplied as a lyophilized powder; sometimes sold as the stabilized arginate salt 'BPC-157 arginate' which has improved aqueous stability.
How it works
Proposed mechanisms include modulation of nitric oxide signaling, upregulation of growth factors (VEGF, FGF, EGF), promotion of angiogenesis, and improved expression of tendon/ligament-relevant receptors. Effects on the dopamine and serotonin systems have also been reported in animal models. Human pharmacokinetics are not well characterized.
Where it's used
Most widely studied in rodent models of tendon, ligament, muscle, gut, and brain injury. ROUTES: most commonly self-administered subcutaneous injection near the area of interest (250-500 mcg, 1-2x/day). Intramuscular injection is also reported. Oral dosing has been used in GI-focused protocols — bioavailability is debated, but its activity in the gut lumen plausibly explains anecdotal benefit there. Topical/transdermal formulations exist but are poorly characterized.
Regulatory status
Not FDA-approved; research compound.
Reconstitution
Lyophilized powder reconstitutes with bacteriostatic water (commonly 2-3 mL per 5 mg vial → 250 mcg per 0.15 mL on a 0.5 mL insulin syringe at U-100). Swirl, do not shake. Refrigerate after reconstitution.
Tracking it
BPC-157 is injectable, so two things matter in a log: when you dosed and where. Rotating sites and writing both down prevents the classic “did I already pin the left side?” problem.
Source
Public reference
Last reviewed 2026-06-11