What it is
A form of vitamin B3 and a precursor to NAD+. Available as a dietary supplement (Niagen) holding FDA New Dietary Ingredient and GRAS status.
How it works
Converted intracellularly via NRK enzymes to NMN and then to NAD+, raising NAD+ levels in tissues. NAD+ supports sirtuin, PARP, and mitochondrial function.
Where it's used
Used as a dietary supplement marketed for NAD+ support and cellular energy. Studied in clinical trials for cardiometabolic and neurologic endpoints.
FDA-approved use
Regulated as a dietary supplement; holds GRAS status as a food ingredient.
Tracking it
Nicotinamide Riboside is oral, which makes consistency the whole game — a simple daily check-off with a reminder beats memory every time. with a half-life of about 8 hours, a dose log also lets a tracker model the relative amount still in your system between doses.
Source
Public reference
Last reviewed 2026-06-11