What it is
A synthetic 37-amino-acid cationic antimicrobial peptide identical to the active C-terminal fragment of human cathelicidin (hCAP-18). Supplied as a lyophilized powder.
How it works
Disrupts microbial membranes via electrostatic interaction with anionic phospholipids. Also modulates innate immune signaling, chemotaxis, and angiogenesis in preclinical models.
Where it's used
Studied in preclinical and early clinical research as an antimicrobial and immunomodulatory peptide.
Regulatory status
Not FDA-approved; research compound.
Reconstitution
Supplied as a lyophilized powder requiring reconstitution with bacteriostatic water prior to use.
Tracking it
LL-37 is injectable, so two things matter in a log: when you dosed and where. Rotating sites and writing both down prevents the classic “did I already pin the left side?” problem.
Source
Public reference
Last reviewed 2026-06-11