What it is
A synthetic tripeptide corresponding to the C-terminal three residues (lysine-proline-valine) of alpha-melanocyte-stimulating hormone.
How it works
Proposed in preclinical studies to enter cells via PepT1 transporters and suppress NF-kappaB signaling and pro-inflammatory cytokine release in epithelial and immune cells.
Where it's used
Studied in preclinical research for anti-inflammatory effects, particularly in the gastrointestinal tract.
Regulatory status
Not FDA-approved; research compound.
Reconstitution
Lyophilized injectable forms require reconstitution with bacteriostatic water; oral capsule forms are pre-mixed.
Tracking it
KPV is oral, which makes consistency the whole game — a simple daily check-off with a reminder beats memory every time.
Source
Public reference
Last reviewed 2026-06-11