Peptides · Oral

KPV

Also known as: Lysine-Proline-Valine · alpha-MSH (11-13)

What it is

A synthetic tripeptide corresponding to the C-terminal three residues (lysine-proline-valine) of alpha-melanocyte-stimulating hormone.

How it works

Proposed in preclinical studies to enter cells via PepT1 transporters and suppress NF-kappaB signaling and pro-inflammatory cytokine release in epithelial and immune cells.

Where it's used

Studied in preclinical research for anti-inflammatory effects, particularly in the gastrointestinal tract.

Regulatory status

Not FDA-approved; research compound.

Reconstitution

Lyophilized injectable forms require reconstitution with bacteriostatic water; oral capsule forms are pre-mixed.

Do the math once, not every pin. The reconstitution calculator converts vial mg + bacteriostatic water into exact syringe units for any target dose.

Tracking it

KPV is oral, which makes consistency the whole game — a simple daily check-off with a reminder beats memory every time.

Source

Public reference

Not medical advice. This page is an educational summary compiled from public sources for people who log what they take. It is not a recommendation to use KPV, a dosing guide, or a substitute for a clinician. How we source →

Last reviewed 2026-06-11