What it is
The copper tripeptide GHK-Cu supplied as a lyophilized powder for subcutaneous injection, as opposed to the pre-mixed topical cosmetic form.
How it works
GHK has high affinity for copper and serves as a carrier; the complex is proposed to modulate genes related to skin remodeling, collagen synthesis, and antioxidant defense in preclinical studies.
Where it's used
Used by some via subcutaneous injection in research/community settings; the same tripeptide is also sold in topical skincare formulations.
Regulatory status
Not FDA-approved as a drug; used as a cosmetic ingredient in topical form.
Reconstitution
Lyophilized injectable forms require reconstitution with bacteriostatic water prior to use.
Tracking it
GHK-Cu is injectable, so two things matter in a log: when you dosed and where. Rotating sites and writing both down prevents the classic “did I already pin the left side?” problem.
Source
Public reference
Last reviewed 2026-06-11