What it is
A combination of the non-proteinogenic amino acid L-citrulline with malic acid, commonly in a 2:1 ratio. Available as oral powders and capsules.
How it works
L-citrulline is converted to L-arginine in the kidneys, raising plasma arginine and supporting nitric oxide synthesis and vasodilation. Malate serves as a tricarboxylic acid cycle intermediate.
Where it's used
Used as a dietary supplement in athletic and resistance-training contexts.
FDA-approved use
Regulated as a dietary supplement.
Tracking it
Citrulline Malate is oral, which makes consistency the whole game — a simple daily check-off with a reminder beats memory every time.
Source
Public reference
Not medical advice. This page is an educational summary compiled from public
sources for people who log what they take. It is not a recommendation to use
Citrulline Malate, a dosing guide, or a substitute for a clinician.
How we source →
Last reviewed 2026-06-11