What it is
A topical solution or foam formulation of minoxidil at 2% or 5% concentration applied directly to the scalp.
How it works
After topical application, scalp sulfotransferases convert minoxidil to its active metabolite minoxidil sulfate, an ATP-sensitive potassium channel opener proposed to prolong the anagen phase of hair growth.
Where it's used
Used in androgenetic alopecia in both sexes. Most widely used over-the-counter treatment for pattern hair loss.
FDA-approved use
Androgenetic alopecia (topical 2% and 5% formulations available over-the-counter).
Tracking it
Logging every administration of Topical Minoxidil builds the record that makes patterns visible. with a half-life of about 4 hours, a dose log also lets a tracker model the relative amount still in your system between doses.
Source
OpenFDA
Last reviewed 2026-06-11