What it is
A vasodilator originally developed as an antihypertensive. Available as a topical solution or foam (Rogaine) and as oral tablets (Loniten).
How it works
An ATP-sensitive potassium channel opener. The active metabolite minoxidil sulfate is believed to prolong the anagen phase of the hair growth cycle; the exact mechanism for hair growth remains incompletely understood.
Where it's used
Topical formulation is used for androgenetic alopecia in both sexes. Oral formulation is approved for severe hypertension and is used off-label at low doses for hair loss.
FDA-approved use
Topical: androgenetic alopecia. Oral: severe hypertension. Low-dose oral use for hair loss is off-label.
Tracking it
Logging every administration of Minoxidil builds the record that makes patterns visible. with a half-life of about 4 hours, a dose log also lets a tracker model the relative amount still in your system between doses.
Source
OpenFDA
Last reviewed 2026-06-11